Images were acquired three hours after injection of 99mTc MDP (methylene diphosphonate). The bone scan shows increased uptake in the skull, spine and long bones. There is also osteomalacia as shown by the symmetrically increased costochondral uptake. Bone scans with the use of 99mTc labelled diphosphonates provides a functional display of skeletal metabolic activity. It may be used in conditions such as osteomalacia, renal osteodystrophy, hyperparathyroidism and osteoporosis, to identify focal lesions, e.g. pseudofractures, vertebral collapse, avascular necrosis and generalised increase in bone activity.
